Significance* is a specialised pharma and academic consultancy, adding value to stakeholders by leading and supporting Evidence Generation Strategies and Real World Evidence initiatives, including RWE study design and execution.

With our extensive experience, we understand firsthand the challenges organizations face in navigating Real World Data to generate top class Real World Evidence and impactful evidence generation strategies. And we are here to help.

Our vision is a future where evidence-driven decisions lead to better health outcomes for patients worldwide.

Generate world class evidence that have an impact

We know first hand the challenges organizations phase on generating a comprehensive and effective evidence generation and strategy. Functional and geographical silos, lengthly processes, unclear frameworks and fragmented internal communication can have significant impact on the quality of the evidence generated as well as pressure resources and budget. Significance can provide expertise and guide you across the full spectrum of RWE initiatives and activities.

Real World Evidence Studies

Design, execution and supervision of RWE studies

Development and review of study documentation

Lead study execution and dissimination of results

Evidence Generation Strategy

Evidence strategy development & implementation

Tactics and integration of cross-functional needs

Development of framework for Evidence Strategies

Processes & RWE awareness

Design, implementation and communication of internal processes and SOPs for RWE

Educational activities and workshops for Real World Data and Evidence

Change management across stakeholders and functions

Learn about our services

Summary Block
This is example content. Double-click here and select a page to feature its content. Learn more
  • Design, protocol, documentation, management and disimmination for results

  • Find evidence gaps, understand the needs

  • What should we know about the services you provide? Better descriptions result in more sales.

  • Item description
  • Item description
Real World Evidence Consultant

About Significance

Evangelos has started Significance after a decade of experience in global pharmaceutical companies, working in Clinical Trials, Real World Data analytics, leading multinational Real World Evidence studies and designing global evidence generation strategies and frameworks.

After working with multiple global companies and collaborating with world’s largest CROs and small consultancies, Evangelos developed an advisory service embodying the traits of an ideal partner: adaptable, understanding of client needs, willing to go the extra mile, and eager to share knowledge. He and Significance team is committed to offering insights, suggestions, and services before payment, avoiding generic solutions for tailored client support.

I started Significance after a decade of experience in global pharmaceutical companies, working in Clinical Trials, Real World Data analytics, leading multinational Real World Evidence studies and designing global evidence generation strategies and frameworks.

As a manager in pharma I hired and worked with a number of external support providers, from world’s largest CROs to small boutique consultancies. From those experiences, I decided to developed an advisory service embodying all the traits of an ideal partner: adaptable, understanding of client needs, willing to go the extra mile, and eager to share knowledge. He and Significance team is committed to offering insights, suggestions, and services before payment, avoiding generic solutions for tailored client support.

Elevating evidence generation for more than 10 years in global and regional functions

Let’s Connect!

Whether you got a Real World Evidence project in mind, need to strategise on your evidence generation or just curious about Real World Evidence and their impact, just drop a message and let’s discuss how we can drive impactful results together.